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title: AI Brush Biopsy Technology Detects Dysplasia - WATS3D | CDx Diagnostics
description: Esophageal cancer is often caught too late. CDx allows physicians to improve patient care with reliable early cancer screening and brush biopsy to preempt cancer.
---

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Healthcare Professionals

# The best patient care is prevention.

Esophageal cancer is one of the deadliest cancers, and screening and surveillance often fail to detect the disease until it’s too late. We’ve created an advanced AI-assisted diagnostic platform that empowers physicians to dramatically increase the detection of Barrett’s esophagus and associated neoplasia before the disease can progress to cancer.

[![placeholder-video-thumbnail](https://www.cdxdiagnostics.com/hubfs/assets/images/placeholder/placeholder-video-thumbnail.jpg)

Testimonial

Watch Javier Sobrado, MD talk about screening test technology (1:51)

](https://vimeo.com/268435756)

## WATS3D helps make esophageal cancer preventable.

![wats3d slide with specimen on microscope](https://www.cdxdiagnostics.com/hubfs/assets/images/images/wats3d-card-featured.jpg)

## WATS3D

This proprietary diagnostic platform combines improved tissue sampling with the latest in artificial intelligence and 3D analysis to help physicians like you evaluate your patients with GERD and Barrett's esophagus, and to prevent esophageal cancer.

[Learn more about WATS3d](https://www.cdxdiagnostics.com/wats3d?hsLang=en)

#### R&D Pipeline

Advancing science throughout the aerodigestive tract. [Learn More](https://www.cdxdiagnostics.com/research-and-development?hsLang=en)

#### OralCDx

Minimally invasive test for the oral cavity. [Learn More](https://www.cdxdiagnostics.com/oralcdx?hsLang=en)

#### EndoCDx

Minimally invasive test for the larynx and pharynx. [Learn More](https://www.cdxdiagnostics.com/endocdx?hsLang=en)

Case Study

## WATS3D Detects High-Grade Dysplasia Missed on Forceps Biopsy

Adjunctive use of AI-enabled diagnostic test helps overcome the sampling error inherent in the Seattle Protocol.

[Read the full case study](https://www.cdxdiagnostics.com/hubfs/assets/resources/Case%20Study%20WATS3D%20Detects%20High-Grade%20Dysplasia%20Missed%20on%20Forceps%20Biopsy.pdf?hsLang=en)

[![Anthony Infantolino, MD FACP, FACG, AGAF, FASGE still image](https://cdn2.hubspot.net/hubfs/6604993/f36e5d88-7033-11ea-bd11-a0369f103266.jpeg)

> Had the WATS3D technology not been used, the local gastroenterologist would have told Robert, ‘you have garden variety Barrett’s, come back in 3 years’ and he would have developed esophageal cancer.” 

Anthony Infantolino, M.D. FACP, FACG, AGAF, FASGE 

](https://vimeo.com/345995350)

![icons-better-sampling](https://www.cdxdiagnostics.com/hubfs/icons-better-sampling.svg)

### See how CDx technology is helping preempt cancer.

[Learn More](https://www.cdxdiagnostics.com/technology?hsLang=en)

## View Our Clinical Data

[ Clinical Data

 2024

### Adjunctive Use of WATS-3D in Symptomatic GERD Patients Increases Detection of Barrett's Esophagus and Dysplasia.

 American Journal of Gastroenterology

 Nicholas J Shaheen, Robert D Odze, Mendel E Singer, William J Salyers, Sachin Srinivasan, Vivek Kaul, Arvind J Trindade, Amit Aravapalli, Robert D Herman, Michael S Smith, Matthew J McKinley 

](https://journals.lww.com/ajg/fulltext/9900/adjunctive_use_of_wide_area_transepithelial.1127.aspx)

[ Clinical Data

 2023

### Benefit of Adjunctive Wide Area Transepithelial Sampling with 3-Dimensional Computer-Assisted Analysis Plus Forceps Biopsy Based on Barrett’s Esophagus Segment Length

 Gastrointestinal Endoscopy

Arvind J. Trindade, MD, Robert D. Odze, MD, FRCPc, Michael S. Smith, MD, MBA, Vivek Kaul, MD 

](https://doi.org/10.1016/j.gie.2023.03.032)

[ Clinical Data

 2022

### Utility of wide-area transepithelial sampling with 3-dimensional computer-assisted analysis as an adjunct to forceps biopsy sampling in the surveillance of patients with Barrett’s esophagus after endoscopic eradication therapy

 iGIE

 F. Scott Corbett, Robert D. Odze, Matthew J. McKinley 

](https://doi.org/10.1016/j.igie.2022.10.011)

## Have a representative contact me

[![It's Easy to Get Started](https://no-cache.hubspot.com/cta/default/6604993/60eccc0c-b748-417e-bc0f-423cdef186db.png)](https://cta-redirect.hubspot.com/cta/redirect/6604993/60eccc0c-b748-417e-bc0f-423cdef186db)

![order kits icon](https://www.cdxdiagnostics.com/hubfs/assets/images/icons/custom/icon-order-kits.svg)

#### Order Kits

Request additional test kits or patient materials.

[Order Now](https://www.cdxdiagnostics.com/2orderkits?hsLang=en)

![support icon](https://www.cdxdiagnostics.com/hubfs/assets/images/icons/custom/icon-support.svg)

#### Support

Let us help you with questions about our products and services.

[Request Support](https://www.cdxdiagnostics.com/support?hsLang=en)

![lab services icon](https://www.cdxdiagnostics.com/hubfs/assets/images/icons/custom/icon-lab-services.svg)

#### Laboratory Services

Learn about the diagnostic assessments used in evaluating specimens.

[Learn More](https://www.cdxdiagnostics.com/laboratory-services?hsLang=en)

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